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Cannabinoid Synergy: The Entourage Effect

At the time of writing this article, there are over 110 phytocannabinoids that have been identified. However, we only know the pharmacological effects of a mere 10% of these cannabinoids.

Phytocannabinoids like CBD work better in whole-plant extracts rather than isolated. The top cannabinoids (along with some known therapeutic properties) that have been studied are

CBC: Anti-fungal, stimulates bone growth, anti-inflammatory, anti-proliferant

CBD: Anandamide activation of CB receptors, turns white fat to brown fat, antiemetic (nausea), neuroprotectant, anti-diarrheal, antibacterial, antipsychotic, anxiolytic, anti-inflammatory, analgesic, vasorelaxant

CBDA: Anti-inflammatory, anti-proliferant, antiemetic

CBDV: Stimulates bone growth

CBG: Anti-bacterial
CBN: Anti-inflammatory, analgesic

THC: Anti/pro-inflammatory, antioxidant, euphoriant, promotes sleep, anxiolytic, analgesic

THCA: Neuroprotectant, promotes well being, mild euphoria, anti-inflammatory, antispasmodic

THCV: suppresses appetite, promotes bone growth, anti-diabetic

On top of our endocannabinoids and cannabinoids derived from cannabis, we have terpenes that add the positive synergy of whole-plant medicine.

The magical and beneficial world of plant life gifts us with terpenes. These precious babies are a vital element in the promotion of balance within the body, flavor, and effect.

Terpenes are the essential building materials that form cannabinoids, provide security to a plant by preventing insect attacks, and they also protect plants from environmental dangers.

These flavorful and aromatic molecules could be considered teeny-tiny superheroes. They are responsible for the variations in cannabis strains making each strain’s taste, smell, and effects unique.

Not only do terpenes supply a fresh bouquet of scents derived from cannabis, but they also affect the creation of the physical and psychoactive effects specific to that strain.  

The entourage effect is the synergistic bond between the phytocannabinoid system, our endocannabinoid system, and terpenes. Together, they fight off illness and injury to promote the restoration of balance within the body.

Studies show there is a synergistic bond between terpenes, phytocannabinoids, and our ECS.


Are There Benefits of Cannabinoid Isolation?

Did you know? At the beginning of cannabis research, CBD was considered an inactive compound of cannabis. As in, it had no benefits at all, let alone medicinal benefits.

Now we know CBD not only possesses many of the same characteristics of cannabis, but it also has its own unique properties too.

Both THC and CBD are known for anti-inflammatory benefits, but the way they produce these benefits is unique. Each cannabinoid does things differently.

When cannabinoids work together, they are a team and produce a more intense and varied array of effects. Due to legal tape surround cannabis and cannabinoid therapy it is much easier to use a CBD oil than it is to source a whole-plant or full-spectrum cannabis oil.

Not to worry! Using a high-quality CBD oil can still help ease your pain and reduce the unwanted symptoms of many conditions both physical and neurological.


What Makes the Entourage Effect so Powerful?

Phytocannabinoids and terpenes from cannabis work better together than they do isolated or synthesized. Effective and powerful results are found when a whole-plant medicine is used.

The entourage effect is the sum of all compounds (small pieces) working together towards one result: help the body restore balance.

Figure out which cannabinoids and terpenes are best suited for your needs and look for a whole-plant medicine with a large ratio of those compounds. Take CBD : THC ratio into consideration.

THC works directly on the receptors in our body whereas CBD takes a backseat approach and enhances our body’s own receptors to function optimally.


Holistic Synergy: Working Together

Why would a CBD company want to discuss THC? Well, the entourage effect that’s why. Cannabis is a fascinating plant with many therapeutic properties.

While you can treat conditions, symptoms and ailments with only CBD and be successful, our ECS is a complex system, and it is only fair to assume it would benefit from phytocannabinoids that act as though they were made to enhance our endocannabinoid system.

Notice how the majority of all cannabinoids we listed above have anti-inflammatory properties? Now combine those cannabinoids with terpenes known to possess the same benefits.

You have on your hands the closest thing to a magic potion that naturally heals you can find in this day and age.

Our All In One Tincture has a unique cannabinoid profile full of terpenes and a variety of cannabinoids that all work together under the entourage effect. Check out our Resource Center to view third-party lab testing results of each batch so that you can view our lovely cannabinoid and terpenoid profile!

Understanding cannabinoid synergy is at its infant stage. We have a small understanding of the potential these phytocompounds possess. More research is being done every day to advance our knowledge, and as always, we will keep you updated!